{"id":3277,"date":"2022-06-14T12:51:38","date_gmt":"2022-06-14T12:51:38","guid":{"rendered":"https:\/\/test.lab.cor2ed.com\/cms\/?post_type=programmes&#038;p=3277"},"modified":"2023-11-17T10:39:10","modified_gmt":"2023-11-17T09:39:10","slug":"gi-connect-update-from-asco-2022","status":"publish","type":"programmes","link":"https:\/\/test.lab.cor2ed.com\/cms\/gi-connect\/programmes\/gi-connect-update-from-asco-2022\/","title":{"rendered":"Update from ASCO 2022 &#8211; Rectal cancer &amp; mCRC"},"content":{"rendered":"<p>Listen to Prof Chiara Cremolini discussing two key abstracts presented at ASCO 2022<\/p>\n<p><\/p>\n<p>Prof. Chiara Cremolini reviews two late-breaking abstracts from the meeting:<\/p>\n<ul>\n<li style=\"list-style-type: none\">\n<ul>\n<li>Single agent PD-1 blockade as curative-intent treatment in mismatch repair deficient locally advanced rectal cancer. Cercek A, et al. Abstract LBA5<\/li>\n<li>Panitumumab plus mFOLFOX6 versus bevacizumab plus mFOLFOX6 as first-line treatment in patients with RAS wild-type mCRC: Results from the phase 3 PARADIGM trial. Yoshino T, et al. Abstract LBA1<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><strong>For news on other ASCO 2022 late-breakers covering sarcoma, breast cancer and multiple myeloma visit <a href=\"https:\/\/test.lab.cor2ed.com\/cms\/n-connect\/programmes\/update-from-asco-2022\/\" target=\"_blank\" rel=\"noopener\">our summary video here<\/a><\/strong><\/p>\n","protected":false},"author":{"id":1032,"first_name":"Miguel","last_name":"Franco","nickname":"miguel.franco@cor2ed.com","email":"miguel.franco@cor2ed.com"},"featured_media":3590,"menu_order":0,"template":"","labels":[12],"keywords":[],"class_list":["post-3277","programmes","type-programmes","status-publish","has-post-thumbnail","hentry","labels-gastrointestinal-oncology-medical-educational-programmes"],"programme_info_project-code":"C2 22-01-01","programme_info_type":"","programme_info_sub-type":"","programme_info_medical-affairs":"","programme_info_series":"","programme_info_series-uid":"","programme_info_series-number":"","programme_info_multiple-media":"","programme_info_subtitle":"<p>Prof. Chiara Cremolini provides her perspectives on two late-breaking abstracts on rectal cancer and metastatic colorectal cancer<\/p>","programme_info_supporter-disclaimer":"","programme_info_acknowledgement":"","programme_info_learning-objetives":"","programme_info_pop-up":"","programme_info_pop-up-text":"","programme_info_pop-up-button-1":"","programme_info_pop-up-button-2":"","programme_therapeutic-areas_therapeutic-areas":["621"],"programme_connect_connect":"791","programme_experts_experts":["31"],"programme_partnerships_partnerships":"","programme_accreditations_accreditations":["191663"],"programme_programmes_programmes":"","programme_connects_connects":"","programme_users_users":"","programme_medias_media_collection":"1","programme_medias_media_show_0":"","programme_medias_media_group_0":"","programme_medias_media_project-code_0":"","programme_medias_media_title_0":"","programme_medias_media_subtitle_0":"","programme_medias_media_description_0":"","programme_medias_media_type_0":"vimeo","programme_medias_media_youtube_0":"fW2cCfYeFHQ","programme_medias_media_vimeo_0":"717474125","programme_medias_media_castos_0":"1156458","programme_medias_media_castos-video_0":"","programme_medias_media_spotify_0":"","programme_medias_media_spotify-video_0":"","programme_medias_media_apple_0":"","programme_medias_media_apple-video_0":"","programme_medias_media_google_0":"","programme_medias_media_google-video_0":"","programme_medias_media_url_0":"","programme_medias_media_scorm_0":"","programme_medias_media_file_0":"","programme_medias_media_duration_0":"2","programme_medias_media_overview_0":"","programme_medias_media_audio-transcript_0":"<p>I am Chiara Cremolini and today I bring to you from ASCO 2022 some interesting results that have been presented.<\/p>\r\n<p><strong>Single agent PD-1 blockade as curative-intent treatment in mismatch repair deficient locally advanced rectal cancer. Cercek A, et al. Abstract LBA5<\/strong><\/p>\r\n<p>In particular an interesting phase 2 trial conducted by the Memorial Sloan Kettering Cancer Center Group was presented today dealing with the treatment of patients with locally advanced rectal cancer, but in particular of patients with deficient mismatch repair or microsatellite unstable tumours.<\/p>\r\n<p>We already knew about the impressive results achieved with immunotherapy in the metastatic setting in dMMR patients. But now we have evidence from 14 patients enrolled in this trial that using immunotherapy may avoid operative management of these patients. Only 14 patients with dMMR rectal cancer in clinical stage 2 or 3 received up to six months of an anti PD-1 monoclonal antibody, dostarlimab, and then underwent a reassessment of their disease by means of pelvic MRI, digital examination and endoscopic assessment. In all of these patients a complete clinical response was observed.<\/p>\r\n<p>So definitely we have only preliminary results at the relatively short follow up but definitely these results are potentially practice changing. Tomorrow in my clinic, I would pretty much love to offer an immunotherapy approach, an immunotherapy strategy to locally advanced dMMR, MSI high patients in order to avoid both chemo radiation and surgery in their therapeutic route.<\/p>\r\n<p><strong><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2201445\">Read the publication online in the NEJM<\/a><\/strong><\/p>\r\n<p><strong>Panitumumab plus mFOLFOX6 versus bevacizumab plus mFOLFOX6 as first-line treatment in patients with RAS wild-type mCRC: Results from the phase 3 PARADIGM trial. Yoshino T, et al. Abstract LBA1<\/strong><\/p>\r\n<p>Another trial in the field of metastatic colorectal cancer was presented in the plenary session. It was the PARADIGM trial, a phase 3 randomised study where RAS wild-type, untreated, un-resectable metastatic colorectal cancer patients who were randomised to receive FOLFOX with either the anti-EGFR panitumumab or the anti-angiogenic bevacizumab.<\/p>\r\n<p>And interestingly, the primary endpoint of this study was the overall survival in the left-sided subgroup, it has shown a clear advantage in terms of overall survival from starting the therapeutic route of these patients with the FOLFOX plus panitumumab instead of bevacizumab with a 3.6 absolute difference in terms of median overall survival and significant benefits in terms of the response rate and the secondary resection of metastasis.<\/p>\r\n<p>Overall, this data confirms that in these patients with the left-sided RAS wild-type tumours starting the therapeutic route with an anti-EGFR based regimen is beneficial, while this is not the the same for patients with the right-sided tumours where overall both doublet plus BEV and doublet plus panitumumab provided really disappointing results and we need something different.<\/p>\r\n<p>So tomorrow my clinical practice will not change too much based on this data because I already used to have doublet plus anti-EGFR as a preferred choice for RAS wild-type left-sided patients but definitely I think now that this is now a solid standard.<\/p>","programme_medias_media_additional-description_0":"","programme_medias_media_supporter-disclaimer_0":"","programme_medias_media_acknowledgement_0":"","programme_medias_media_learning-objetives_0":"","programme_medias_media_custom-description-title_0":"","programme_medias_media_custom-description-text_0":"","programme_medias_media_connect_0":"","programme_medias_media_experts_0":"","programme_medias_media_partnerships_0":"","programme_medias_media_connects_0":"","programme_medias_media_0_documents_collection":"","programme_medias_media_0_documents_file_0":"","programme_medias_media_0_documents_button_0":"","programme_medias_media_0_documents_file_1":"","programme_medias_media_0_documents_button_1":"","programme_medias_media_0_documents_file_2":"","programme_medias_media_0_documents_button_2":"","programme_medias_media_0_documents_file_3":"","programme_medias_media_0_documents_button_3":"","programme_medias_media_0_documents_file_4":"","programme_medias_media_0_documents_button_4":"","programme_medias_media_0_documents_file_5":"","programme_medias_media_0_documents_button_5":"","programme_medias_media_0_documents_file_6":"","programme_medias_media_0_documents_button_6":"","programme_medias_media_0_documents_file_7":"","programme_medias_media_0_documents_button_7":"","programme_medias_media_0_documents_file_8":"","programme_medias_media_0_documents_button_8":"","programme_medias_media_0_documents_file_9":"","programme_medias_media_0_documents_button_9":"","programme_medias_media_0_buttons_collection":"","programme_medias_media_0_buttons_text_0":"","programme_medias_media_0_buttons_url_0":"","programme_medias_media_0_buttons_text_1":"","programme_medias_media_0_buttons_url_1":"","programme_medias_media_0_buttons_text_2":"","programme_medias_media_0_buttons_url_2":"","programme_medias_media_0_buttons_text_3":"","programme_medias_media_0_buttons_url_3":"","programme_medias_media_0_buttons_text_4":"","programme_medias_media_0_buttons_url_4":"","programme_medias_media_0_buttons_text_5":"","programme_medias_media_0_buttons_url_5":"","programme_medias_media_0_buttons_text_6":"","programme_medias_media_0_buttons_url_6":"","programme_medias_media_0_buttons_text_7":"","programme_medias_media_0_buttons_url_7":"","programme_medias_media_0_buttons_text_8":"","programme_medias_media_0_buttons_url_8":"","programme_medias_media_0_buttons_text_9":"","programme_medias_media_0_buttons_url_9":"","programme_medias_media_0_social-media-url_collection":"","programme_medias_media_0_social-media-url_url_0":"","programme_medias_media_0_social-media-url_url_1":"","programme_medias_media_0_social-media-url_url_2":"","programme_medias_media_0_social-media-url_url_3":"","programme_medias_media_0_social-media-url_url_4":"","programme_medias_media_0_social-media-url_url_5":"","programme_medias_media_0_social-media-url_url_6":"","programme_medias_media_0_social-media-url_url_7":"","programme_medias_media_0_social-media-url_url_8":"","programme_medias_media_0_social-media-url_url_9":"","programme_medias_media_show_1":"","programme_medias_media_group_1":"","programme_medias_media_project-code_1":"","programme_medias_media_title_1":"","programme_medias_media_subtitle_1":"","programme_medias_media_description_1":"","programme_medias_media_type_1":"","programme_medias_media_youtube_1":"","programme_medias_media_vimeo_1":"","programme_medias_media_castos_1":"","programme_medias_media_castos-video_1":"","programme_medias_media_spotify_1":"","programme_medias_media_spotify-video_1":"","programme_medias_media_apple_1":"","programme_medias_media_apple-video_1":"","programme_medias_media_google_1":"","programme_medias_media_google-video_1":"","programme_medias_media_url_1":"","programme_medias_media_scorm_1":"","programme_medias_media_file_1":"","programme_medias_media_duration_1":"","programme_medias_media_overview_1":"","programme_medias_media_audio-transcript_1":"","programme_medias_media_additional-description_1":"","programme_medias_media_supporter-disclaimer_1":"","programme_medias_media_acknowledgement_1":"","programme_medias_media_learning-objetives_1":"","programme_medias_media_custom-description-title_1":"","programme_medias_media_custom-description-text_1":"","programme_medias_media_connect_1":"","programme_medias_media_experts_1":"","programme_medias_media_partnerships_1":"","programme_medias_media_connects_1":"","programme_medias_media_1_documents_collection":"","programme_medias_media_1_documents_file_0":"","programme_medias_media_1_documents_button_0":"","programme_medias_media_1_documents_file_1":"","programme_medias_media_1_documents_button_1":"","programme_medias_media_1_documents_file_2":"","programme_medias_media_1_documents_button_2":"","programme_medias_media_1_documents_file_3":"","programme_medias_media_1_documents_button_3":"","programme_medias_media_1_documents_file_4":"","programme_medias_media_1_documents_button_4":"","programme_medias_media_1_documents_file_5":"","programme_medias_media_1_documents_button_5":"","programme_medias_media_1_documents_file_6":"","programme_medias_media_1_documents_button_6":"","programme_medias_media_1_documents_file_7":"","programme_medias_media_1_documents_button_7":"","programme_medias_media_1_documents_file_8":"","programme_medias_media_1_documents_button_8":"","programme_medias_media_1_documents_file_9":"","programme_medias_media_1_documents_button_9":"","programme_medias_media_1_buttons_collection":"","programme_medias_media_1_buttons_text_0":"","programme_medias_media_1_buttons_url_0":"","programme_medias_media_1_buttons_text_1":"","programme_medias_media_1_buttons_url_1":"","programme_medias_media_1_buttons_text_2":"","programme_medias_media_1_buttons_url_2":"","programme_medias_media_1_buttons_text_3":"","programme_medias_media_1_buttons_url_3":"","programme_medias_media_1_buttons_text_4":"","programme_medias_media_1_buttons_url_4":"","programme_medias_media_1_buttons_text_5":"","programme_medias_media_1_buttons_url_5":"","programme_medias_media_1_buttons_text_6":"","programme_medias_media_1_buttons_url_6":"","programme_medias_media_1_buttons_text_7":"","programme_medias_media_1_buttons_url_7":"","programme_medias_media_1_buttons_text_8":"","programme_medias_media_1_buttons_url_8":"","programme_medias_media_1_buttons_text_9":"","programme_medias_media_1_buttons_url_9":"","programme_medias_media_1_social-media-url_collection":"","programme_medias_media_1_social-media-url_url_0":"","programme_medias_media_1_social-media-url_url_1":"","programme_medias_media_1_social-media-url_url_2":"","programme_medias_media_1_social-media-url_url_3":"","programme_medias_media_1_social-media-url_url_4":"","programme_medias_media_1_social-media-url_url_5":"","programme_medias_media_1_social-media-url_url_6":"","programme_medias_media_1_social-media-url_url_7":"","programme_medias_media_1_social-media-url_url_8":"","programme_medias_media_1_social-media-url_url_9":"","programme_medias_media_show_2":"","programme_medias_media_group_2":"","programme_medias_media_project-code_2":"","programme_medias_media_title_2":"","programme_medias_media_subtitle_2":"","programme_medias_media_description_2":"","programme_medias_media_type_2":"","programme_medias_media_youtube_2":"","programme_medias_media_vimeo_2":"","programme_medias_media_castos_2":"","programme_medias_media_castos-video_2":"","programme_medias_media_spotify_2":"","programme_medias_media_spotify-video_2":"","programme_medias_media_apple_2":"","programme_medias_media_apple-video_2":"","programme_medias_media_google_2":"","programme_medias_media_google-video_2":"","programme_medias_media_url_2":"","programme_medias_media_scorm_2":"","programme_medias_media_file_2":"","programme_medias_media_duration_2":"","programme_medias_media_overview_2":"","programme_medias_media_audio-transcript_2":"","programme_medias_media_additional-description_2":"","programme_medias_media_supporter-disclaimer_2":"","programme_medias_media_acknowledgement_2":"","programme_medias_media_learning-objetives_2":"","programme_medias_media_custom-description-title_2":"","programme_medias_media_custom-description-text_2":"","programme_medias_media_connect_2":"","programme_medias_media_experts_2":"","programme_medias_media_partnerships_2":"","programme_medias_media_connects_2":"","programme_medias_media_2_documents_collection":"","programme_medias_media_2_documents_file_0":"","programme_medias_media_2_documents_button_0":"","programme_medias_media_2_documents_file_1":"","programme_medias_media_2_documents_button_1":"","programme_medias_media_2_documents_file_2":"","programme_medias_media_2_documents_button_2":"","programme_medias_media_2_documents_file_3":"","programme_medias_media_2_documents_button_3":"","programme_medias_media_2_documents_file_4":"","programme_medias_media_2_documents_button_4":"","programme_medias_media_2_documents_file_5":"","programme_medias_media_2_documents_button_5":"","programme_medias_media_2_documents_file_6":"","programme_medias_media_2_documents_button_6":"","programme_medias_media_2_documents_file_7":"","programme_medias_media_2_documents_button_7":"","programme_medias_media_2_documents_file_8":"","programme_medias_media_2_documents_button_8":"","programme_medias_media_2_documents_file_9":"","programme_medias_media_2_documents_button_9":"","programme_medias_media_2_buttons_collection":"","programme_medias_media_2_buttons_text_0":"","programme_medias_media_2_buttons_url_0":"","programme_medias_media_2_buttons_text_1":"","programme_medias_media_2_buttons_url_1":"","programme_medias_media_2_buttons_text_2":"","programme_medias_media_2_buttons_url_2":"","programme_medias_media_2_buttons_text_3":"","programme_medias_media_2_buttons_url_3":"","programme_medias_media_2_buttons_text_4":"","programme_medias_media_2_buttons_url_4":"","programme_medias_media_2_buttons_text_5":"","programme_medias_media_2_buttons_url_5":"","programme_medias_media_2_buttons_text_6":"","programme_medias_media_2_buttons_url_6":"","programme_medias_media_2_buttons_text_7":"","programme_medias_media_2_buttons_url_7":"","programme_medias_media_2_buttons_text_8":"","programme_medias_media_2_buttons_url_8":"","programme_medias_media_2_buttons_text_9":"","programme_medias_media_2_buttons_url_9":"","programme_medias_media_2_social-media-url_collection":"","programme_medias_media_2_social-media-url_url_0":"","programme_medias_media_2_social-media-url_url_1":"","programme_medias_media_2_social-media-url_url_2":"","programme_medias_media_2_social-media-url_url_3":"","programme_medias_media_2_social-media-url_url_4":"","programme_medias_media_2_social-media-url_url_5":"","programme_medias_media_2_social-media-url_url_6":"","programme_medias_media_2_social-media-url_url_7":"","programme_medias_media_2_social-media-url_url_8":"","programme_medias_media_2_social-media-url_url_9":"","programme_medias_media_show_3":"","programme_medias_media_group_3":"","programme_medias_media_project-code_3":"","programme_medias_media_title_3":"","programme_medias_media_subtitle_3":"","programme_medias_media_description_3":"","programme_medias_media_type_3":"","programme_medias_media_youtube_3":"","programme_medias_media_vimeo_3":"","programme_medias_media_castos_3":"","programme_medias_media_castos-video_3":"","programme_medias_media_spotify_3":"","programme_medias_media_spotify-video_3":"","programme_medias_media_apple_3":"","programme_medias_media_apple-video_3":"","programme_medias_media_google_3":"","programme_medias_media_google-video_3":"","programme_medias_media_url_3":"","programme_medias_media_scorm_3":"","programme_medias_media_file_3":"","programme_medias_media_duration_3":"","programme_medias_media_overview_3":"","programme_medias_media_audio-transcript_3":"","programme_medias_media_additional-description_3":"","programme_medias_media_supporter-disclaimer_3":"","programme_medias_media_acknowledgement_3":"","programme_medias_media_learning-objetives_3":"","programme_medias_media_custom-description-title_3":"","programme_medias_media_custom-description-text_3":"","programme_medias_media_connect_3":"","programme_medias_media_experts_3":"","programme_medias_media_partnerships_3":"","programme_medias_media_connects_3":"","programme_medias_media_3_documents_collection":"","programme_medias_media_3_documents_file_0":"","programme_medias_media_3_documents_button_0":"","programme_medias_media_3_documents_file_1":"","programme_medias_media_3_documents_button_1":"","programme_medias_media_3_documents_file_2":"","programme_medias_media_3_documents_button_2":"","programme_medias_media_3_documents_file_3":"","programme_medias_media_3_documents_button_3":"","programme_medias_media_3_documents_file_4":"","programme_medias_media_3_documents_button_4":"","programme_medias_media_3_documents_file_5":"","programme_medias_media_3_documents_button_5":"","programme_medias_media_3_documents_file_6":"","programme_medias_media_3_documents_button_6":"","programme_medias_media_3_documents_file_7":"","programme_medias_media_3_documents_button_7":"","programme_medias_media_3_documents_file_8":"","programme_medias_media_3_documents_button_8":"","programme_medias_media_3_documents_file_9":"","programme_medias_media_3_documents_button_9":"","programme_medias_media_3_buttons_collection":"","programme_medias_media_3_buttons_text_0":"","programme_medias_media_3_buttons_url_0":"","programme_medias_media_3_buttons_text_1":"","programme_medias_media_3_buttons_url_1":"","programme_medias_media_3_buttons_text_2":"","programme_medias_media_3_buttons_url_2":"","programme_medias_media_3_buttons_text_3":"","programme_medias_media_3_buttons_url_3":"","programme_medias_media_3_buttons_text_4":"","programme_medias_media_3_buttons_url_4":"","programme_medias_media_3_buttons_text_5":"","programme_medias_media_3_buttons_url_5":"","programme_medias_media_3_buttons_text_6":"","programme_medias_media_3_buttons_url_6":"","programme_medias_media_3_buttons_text_7":"","programme_medias_media_3_buttons_url_7":"","programme_medias_media_3_buttons_text_8":"","programme_medias_media_3_buttons_url_8":"","programme_medias_media_3_buttons_text_9":"","programme_medias_media_3_buttons_url_9":"","programme_medias_media_3_social-media-url_collection":"","programme_medias_media_3_social-media-url_url_0":"","programme_medias_media_3_social-media-url_url_1":"","programme_medias_media_3_social-media-url_url_2":"","programme_medias_media_3_social-media-url_url_3":"","programme_medias_media_3_social-media-url_url_4":"","programme_medias_media_3_social-media-url_url_5":"","programme_medias_media_3_social-media-url_url_6":"","programme_medias_media_3_social-media-url_url_7":"","programme_medias_media_3_social-media-url_url_8":"","programme_medias_media_3_social-media-url_url_9":"","programme_medias_media_show_4":"","programme_medias_media_group_4":"","programme_medias_media_project-code_4":"","programme_medias_media_title_4":"","programme_medias_media_subtitle_4":"","programme_medias_media_description_4":"","programme_medias_media_type_4":"","programme_medias_media_youtube_4":"","programme_medias_media_vimeo_4":"","programme_medias_media_castos_4":"","programme_medias_media_castos-video_4":"","programme_medias_media_spotify_4":"","programme_medias_media_spotify-video_4":"","programme_medias_media_apple_4":"","programme_medias_media_apple-video_4":"","programme_medias_media_google_4":"","programme_medias_media_google-video_4":"","programme_medias_media_url_4":"","programme_medias_media_scorm_4":"","programme_medias_media_file_4":"","programme_medias_media_duration_4":"","programme_medias_media_overview_4":"","programme_medias_media_audio-transcript_4":"","programme_medias_media_additional-description_4":"","programme_medias_media_supporter-disclaimer_4":"","programme_medias_media_acknowledgement_4":"","programme_medias_media_learning-objetives_4":"","programme_medias_media_custom-description-title_4":"","programme_medias_media_custom-description-text_4":"","programme_medias_media_connect_4":"","programme_medias_media_experts_4":"","programme_medias_media_partnerships_4":"","programme_medias_media_connects_4":"","programme_medias_media_4_documents_collection":"","programme_medias_media_4_documents_file_0":"","programme_medias_media_4_documents_button_0":"","programme_medias_media_4_documents_file_1":"","programme_medias_media_4_documents_button_1":"","programme_medias_media_4_documents_file_2":"","programme_medias_media_4_documents_button_2":"","programme_medias_media_4_documents_file_3":"","programme_medias_media_4_documents_button_3":"","programme_medias_media_4_documents_file_4":"","programme_medias_media_4_documents_button_4":"","programme_medias_media_4_documents_file_5":"","programme_medias_media_4_documents_button_5":"","programme_medias_media_4_documents_file_6":"","programme_medias_media_4_documents_button_6":"","programme_medias_media_4_documents_file_7":"","programme_medias_media_4_documents_button_7":"","programme_medias_media_4_documents_file_8":"","programme_medias_media_4_documents_button_8":"","programme_medias_media_4_documents_file_9":"","programme_medias_media_4_documents_button_9":"","programme_medias_media_4_buttons_collection":"","programme_medias_media_4_buttons_text_0":"","programme_medias_media_4_buttons_url_0":"","programme_medias_media_4_buttons_text_1":"","programme_medias_media_4_buttons_url_1":"","programme_medias_media_4_buttons_text_2":"","programme_medias_media_4_buttons_url_2":"","programme_medias_media_4_buttons_text_3":"","programme_medias_media_4_buttons_url_3":"","programme_medias_media_4_buttons_text_4":"","programme_medias_media_4_buttons_url_4":"","programme_medias_media_4_buttons_text_5":"","programme_medias_media_4_buttons_url_5":"","programme_medias_media_4_buttons_text_6":"","programme_medias_media_4_buttons_url_6":"","programme_medias_media_4_buttons_text_7":"","programme_medias_media_4_buttons_url_7":"","programme_medias_media_4_buttons_text_8":"","programme_medias_media_4_buttons_url_8":"","programme_medias_media_4_buttons_text_9":"","programme_medias_media_4_buttons_url_9":"","programme_medias_media_4_social-media-url_collection":"","programme_medias_media_4_social-media-url_url_0":"","programme_medias_media_4_social-media-url_url_1":"","programme_medias_media_4_social-media-url_url_2":"","programme_medias_media_4_social-media-url_url_3":"","programme_medias_media_4_social-media-url_url_4":"","programme_medias_media_4_social-media-url_url_5":"","programme_medias_media_4_social-media-url_url_6":"","programme_medias_media_4_social-media-url_url_7":"","programme_medias_media_4_social-media-url_url_8":"","programme_medias_media_4_social-media-url_url_9":"","programme_medias_media_show_5":"","programme_medias_media_group_5":"","programme_medias_media_project-code_5":"","programme_medias_media_title_5":"","programme_medias_media_subtitle_5":"","programme_medias_media_description_5":"","programme_medias_media_type_5":"","programme_medias_media_youtube_5":"","programme_medias_media_vimeo_5":"","programme_medias_media_castos_5":"","programme_medias_media_castos-video_5":"","programme_medias_media_spotify_5":"","programme_medias_media_spotify-video_5":"","programme_medias_media_apple_5":"","programme_medias_media_apple-video_5":"","programme_medias_media_google_5":"","programme_medias_media_google-video_5":"","programme_medias_media_url_5":"","programme_medias_media_scorm_5":"","programme_medias_media_file_5":"","programme_medias_media_duration_5":"","programme_medias_media_overview_5":"","programme_medias_media_audio-transcript_5":"","programme_medias_media_additional-description_5":"","programme_medias_media_supporter-disclaimer_5":"","programme_medias_media_acknowledgement_5":"","programme_medias_media_learning-objetives_5":"","programme_medias_media_custom-description-title_5":"","programme_medias_media_custom-description-text_5":"","programme_medias_media_connect_5":"","programme_medias_media_experts_5":"","programme_medias_media_partnerships_5":"","programme_medias_media_connects_5":"","programme_medias_media_5_documents_collection":"","programme_medias_media_5_documents_file_0":"","programme_medias_media_5_documents_button_0":"","programme_medias_media_5_documents_file_1":"","programme_medias_media_5_documents_button_1":"","programme_medias_media_5_documents_file_2":"","programme_medias_media_5_documents_button_2":"","programme_medias_media_5_documents_file_3":"","programme_medias_media_5_documents_button_3":"","programme_medias_media_5_documents_file_4":"","programme_medias_media_5_documents_button_4":"","programme_medias_media_5_documents_file_5":"","programme_medias_media_5_documents_button_5":"","programme_medias_media_5_documents_file_6":"","programme_medias_media_5_documents_button_6":"","programme_medias_media_5_documents_file_7":"","programme_medias_media_5_documents_button_7":"","programme_medias_media_5_documents_file_8":"","programme_medias_media_5_documents_button_8":"","programme_medias_media_5_documents_file_9":"","programme_medias_media_5_documents_button_9":"","programme_medias_media_5_buttons_collection":"","programme_medias_media_5_buttons_text_0":"","programme_medias_media_5_buttons_url_0":"","programme_medias_media_5_buttons_text_1":"","programme_medias_media_5_buttons_url_1":"","programme_medias_media_5_buttons_text_2":"","programme_medias_media_5_buttons_url_2":"","programme_medias_media_5_buttons_text_3":"","programme_medias_media_5_buttons_url_3":"","programme_medias_media_5_buttons_text_4":"","programme_medias_media_5_buttons_url_4":"","programme_medias_media_5_buttons_text_5":"","programme_medias_media_5_buttons_url_5":"","programme_medias_media_5_buttons_text_6":"","programme_medias_media_5_buttons_url_6":"","programme_medias_media_5_buttons_text_7":"","programme_medias_media_5_buttons_url_7":"","programme_medias_media_5_buttons_text_8":"","programme_medias_media_5_buttons_url_8":"","programme_medias_media_5_buttons_text_9":"","programme_medias_media_5_buttons_url_9":"","programme_medias_media_5_social-media-url_collection":"","programme_medias_media_5_social-media-url_url_0":"","programme_medias_media_5_social-media-url_url_1":"","programme_medias_media_5_social-media-url_url_2":"","programme_medias_media_5_social-media-url_url_3":"","programme_medias_media_5_social-media-url_url_4":"","programme_medias_media_5_social-media-url_url_5":"","programme_medias_media_5_social-media-url_url_6":"","programme_medias_media_5_social-media-url_url_7":"","programme_medias_media_5_social-media-url_url_8":"","programme_medias_media_5_social-media-url_url_9":"","programme_medias_media_show_6":"","programme_medias_media_group_6":"","programme_medias_media_project-code_6":"","programme_medias_media_title_6":"","programme_medias_media_subtitle_6":"","programme_medias_media_description_6":"","programme_medias_media_type_6":"","programme_medias_media_youtube_6":"","programme_medias_media_vimeo_6":"","programme_medias_media_castos_6":"","programme_medias_media_castos-video_6":"","programme_medias_media_spotify_6":"","programme_medias_media_spotify-video_6":"","programme_medias_media_apple_6":"","programme_medias_media_apple-video_6":"","programme_medias_media_google_6":"","programme_medias_media_google-video_6":"","programme_medias_media_url_6":"","programme_medias_media_scorm_6":"","programme_medias_media_file_6":"","programme_medias_media_duration_6":"","programme_medias_media_overview_6":"","programme_medias_media_audio-transcript_6":"","programme_medias_media_additional-description_6":"","programme_medias_media_supporter-disclaimer_6":"","programme_medias_media_acknowledgement_6":"","programme_medias_media_learning-objetives_6":"","programme_medias_media_custom-description-title_6":"","programme_medias_media_custom-description-text_6":"","programme_medias_media_connect_6":"","programme_medias_media_experts_6":"","programme_medias_media_partnerships_6":"","programme_medias_media_connects_6":"","programme_medias_media_6_documents_collection":"","programme_medias_media_6_documents_file_0":"","programme_medias_media_6_documents_button_0":"","programme_medias_media_6_documents_file_1":"","programme_medias_media_6_documents_button_1":"","programme_medias_media_6_documents_file_2":"","programme_medias_media_6_documents_button_2":"","programme_medias_media_6_documents_file_3":"","programme_medias_media_6_documents_button_3":"","programme_medias_media_6_documents_file_4":"","programme_medias_media_6_documents_button_4":"","programme_medias_media_6_documents_file_5":"","programme_medias_media_6_documents_button_5":"","programme_medias_media_6_documents_file_6":"","programme_medias_media_6_documents_button_6":"","programme_medias_media_6_documents_file_7":"","programme_medias_media_6_documents_button_7":"","programme_medias_media_6_documents_file_8":"","programme_medias_media_6_documents_button_8":"","programme_medias_media_6_documents_file_9":"","programme_medias_media_6_documents_button_9":"","programme_medias_media_6_buttons_collection":"","programme_medias_media_6_buttons_text_0":"","programme_medias_media_6_buttons_url_0":"","programme_medias_media_6_buttons_text_1":"","programme_medias_media_6_buttons_url_1":"","programme_medias_media_6_buttons_text_2":"","programme_medias_media_6_buttons_url_2":"","programme_medias_media_6_buttons_text_3":"","programme_medias_media_6_buttons_url_3":"","programme_medias_media_6_buttons_text_4":"","programme_medias_media_6_buttons_url_4":"","programme_medias_media_6_buttons_text_5":"","programme_medias_media_6_buttons_url_5":"","programme_medias_media_6_buttons_text_6":"","programme_medias_media_6_buttons_url_6":"","programme_medias_media_6_buttons_text_7":"","programme_medias_media_6_buttons_url_7":"","programme_medias_media_6_buttons_text_8":"","programme_medias_media_6_buttons_url_8":"","programme_medias_media_6_buttons_text_9":"","programme_medias_media_6_buttons_url_9":"","programme_medias_media_6_social-media-url_collection":"","programme_medias_media_6_social-media-url_url_0":"","programme_medias_media_6_social-media-url_url_1":"","programme_medias_media_6_social-media-url_url_2":"","programme_medias_media_6_social-media-url_url_3":"","programme_medias_media_6_social-media-url_url_4":"","programme_medias_media_6_social-media-url_url_5":"","programme_medias_media_6_social-media-url_url_6":"","programme_medias_media_6_social-media-url_url_7":"","programme_medias_media_6_social-media-url_url_8":"","programme_medias_media_6_social-media-url_url_9":"","programme_medias_media_show_7":"","programme_medias_media_group_7":"","programme_medias_media_project-code_7":"","programme_medias_media_title_7":"","programme_medias_media_subtitle_7":"","programme_medias_media_description_7":"","programme_medias_media_type_7":"","programme_medias_media_youtube_7":"","programme_medias_media_vimeo_7":"","programme_medias_media_castos_7":"","programme_medias_media_castos-video_7":"","programme_medias_media_spotify_7":"","programme_medias_media_spotify-video_7":"","programme_medias_media_apple_7":"","programme_medias_media_apple-video_7":"","programme_medias_media_google_7":"","programme_medias_media_google-video_7":"","programme_medias_media_url_7":"","programme_medias_media_scorm_7":"","programme_medias_media_file_7":"","programme_medias_media_duration_7":"","programme_medias_media_overview_7":"","programme_medias_media_audio-transcript_7":"","programme_medias_media_additional-description_7":"","programme_medias_media_supporter-disclaimer_7":"","programme_medias_media_acknowledgement_7":"","programme_medias_media_learning-objetives_7":"","programme_medias_media_custom-description-title_7":"","programme_medias_media_custom-description-text_7":"","programme_medias_media_connect_7":"","programme_medias_media_experts_7":"","programme_medias_media_partnerships_7":"","programme_medias_media_connects_7":"","programme_medias_media_7_documents_collection":"","programme_medias_media_7_documents_file_0":"","programme_medias_media_7_documents_button_0":"","programme_medias_media_7_documents_file_1":"","programme_medias_media_7_documents_button_1":"","programme_medias_media_7_documents_file_2":"","programme_medias_media_7_documents_button_2":"","programme_medias_media_7_documents_file_3":"","programme_medias_media_7_documents_button_3":"","programme_medias_media_7_documents_file_4":"","programme_medias_media_7_documents_button_4":"","programme_medias_media_7_documents_file_5":"","programme_medias_media_7_documents_button_5":"","programme_medias_media_7_documents_file_6":"","programme_medias_media_7_documents_button_6":"","programme_medias_media_7_documents_file_7":"","programme_medias_media_7_documents_button_7":"","programme_medias_media_7_documents_file_8":"","programme_medias_media_7_documents_button_8":"","programme_medias_media_7_documents_file_9":"","programme_medias_media_7_documents_button_9":"","programme_medias_media_7_buttons_collection":"","programme_medias_media_7_buttons_text_0":"","programme_medias_media_7_buttons_url_0":"","programme_medias_media_7_buttons_text_1":"","programme_medias_media_7_buttons_url_1":"","programme_medias_media_7_buttons_text_2":"","programme_medias_media_7_buttons_url_2":"","programme_medias_media_7_buttons_text_3":"","programme_medias_media_7_buttons_url_3":"","programme_medias_media_7_buttons_text_4":"","programme_medias_media_7_buttons_url_4":"","programme_medias_media_7_buttons_text_5":"","programme_medias_media_7_buttons_url_5":"","programme_medias_media_7_buttons_text_6":"","programme_medias_media_7_buttons_url_6":"","programme_medias_media_7_buttons_text_7":"","programme_medias_media_7_buttons_url_7":"","programme_medias_media_7_buttons_text_8":"","programme_medias_media_7_buttons_url_8":"","programme_medias_media_7_buttons_text_9":"","programme_medias_media_7_buttons_url_9":"","programme_medias_media_7_social-media-url_collection":"","programme_medias_media_7_social-media-url_url_0":"","programme_medias_media_7_social-media-url_url_1":"","programme_medias_media_7_social-media-url_url_2":"","programme_medias_media_7_social-media-url_url_3":"","programme_medias_media_7_social-media-url_url_4":"","programme_medias_media_7_social-media-url_url_5":"","programme_medias_media_7_social-media-url_url_6":"","programme_medias_media_7_social-media-url_url_7":"","programme_medias_media_7_social-media-url_url_8":"","programme_medias_media_7_social-media-url_url_9":"","programme_medias_media_show_8":"","programme_medias_media_group_8":"","programme_medias_media_project-code_8":"","programme_medias_media_title_8":"","programme_medias_media_subtitle_8":"","programme_medias_media_description_8":"","programme_medias_media_type_8":"","programme_medias_media_youtube_8":"","programme_medias_media_vimeo_8":"","programme_medias_media_castos_8":"","programme_medias_media_castos-video_8":"","programme_medias_media_spotify_8":"","programme_medias_media_spotify-video_8":"","programme_medias_media_apple_8":"","programme_medias_media_apple-video_8":"","programme_medias_media_google_8":"","programme_medias_media_google-video_8":"","programme_medias_media_url_8":"","programme_medias_media_scorm_8":"","programme_medias_media_file_8":"","programme_medias_media_duration_8":"","programme_medias_media_overview_8":"","programme_medias_media_audio-transcript_8":"","programme_medias_media_additional-description_8":"","programme_medias_media_supporter-disclaimer_8":"","programme_medias_media_acknowledgement_8":"","programme_medias_media_learning-objetives_8":"","programme_medias_media_custom-description-title_8":"","programme_medias_media_custom-description-text_8":"","programme_medias_media_connect_8":"","programme_medias_media_experts_8":"","programme_medias_media_partnerships_8":"","programme_medias_media_connects_8":"","programme_medias_media_8_documents_collection":"","programme_medias_media_8_documents_file_0":"","programme_medias_media_8_documents_button_0":"","programme_medias_media_8_documents_file_1":"","programme_medias_media_8_documents_button_1":"","programme_medias_media_8_documents_file_2":"","programme_medias_media_8_documents_button_2":"","programme_medias_media_8_documents_file_3":"","programme_medias_media_8_documents_button_3":"","programme_medias_media_8_documents_file_4":"","programme_medias_media_8_documents_button_4":"","programme_medias_media_8_documents_file_5":"","programme_medias_media_8_documents_button_5":"","programme_medias_media_8_documents_file_6":"","programme_medias_media_8_documents_button_6":"","programme_medias_media_8_documents_file_7":"","programme_medias_media_8_documents_button_7":"","programme_medias_media_8_documents_file_8":"","programme_medias_media_8_documents_button_8":"","programme_medias_media_8_documents_file_9":"","programme_medias_media_8_documents_button_9":"","programme_medias_media_8_buttons_collection":"","programme_medias_media_8_buttons_text_0":"","programme_medias_media_8_buttons_url_0":"","programme_medias_media_8_buttons_text_1":"","programme_medias_media_8_buttons_url_1":"","programme_medias_media_8_buttons_text_2":"","programme_medias_media_8_buttons_url_2":"","programme_medias_media_8_buttons_text_3":"","programme_medias_media_8_buttons_url_3":"","programme_medias_media_8_buttons_text_4":"","programme_medias_media_8_buttons_url_4":"","programme_medias_media_8_buttons_text_5":"","programme_medias_media_8_buttons_url_5":"","programme_medias_media_8_buttons_text_6":"","programme_medias_media_8_buttons_url_6":"","programme_medias_media_8_buttons_text_7":"","programme_medias_media_8_buttons_url_7":"","programme_medias_media_8_buttons_text_8":"","programme_medias_media_8_buttons_url_8":"","programme_medias_media_8_buttons_text_9":"","programme_medias_media_8_buttons_url_9":"","programme_medias_media_8_social-media-url_collection":"","programme_medias_media_8_social-media-url_url_0":"","programme_medias_media_8_social-media-url_url_1":"","programme_medias_media_8_social-media-url_url_2":"","programme_medias_media_8_social-media-url_url_3":"","programme_medias_media_8_social-media-url_url_4":"","programme_medias_media_8_social-media-url_url_5":"","programme_medias_media_8_social-media-url_url_6":"","programme_medias_media_8_social-media-url_url_7":"","programme_medias_media_8_social-media-url_url_8":"","programme_medias_media_8_social-media-url_url_9":"","programme_medias_media_show_9":"","programme_medias_media_group_9":"","programme_medias_media_project-code_9":"","programme_medias_media_title_9":"","programme_medias_media_subtitle_9":"","programme_medias_media_description_9":"","programme_medias_media_type_9":"","programme_medias_media_youtube_9":"","programme_medias_media_vimeo_9":"","programme_medias_media_castos_9":"","programme_medias_media_castos-video_9":"","programme_medias_media_spotify_9":"","programme_medias_media_spotify-video_9":"","programme_medias_media_apple_9":"","programme_medias_media_apple-video_9":"","programme_medias_media_google_9":"","programme_medias_media_google-video_9":"","programme_medias_media_url_9":"","programme_medias_media_scorm_9":"","programme_medias_media_file_9":"","programme_medias_media_duration_9":"","programme_medias_media_overview_9":"","programme_medias_media_audio-transcript_9":"","programme_medias_media_additional-description_9":"","programme_medias_media_supporter-disclaimer_9":"","programme_medias_media_acknowledgement_9":"","programme_medias_media_learning-objetives_9":"","programme_medias_media_custom-description-title_9":"","programme_medias_media_custom-description-text_9":"","programme_medias_media_connect_9":"","programme_medias_media_experts_9":"","programme_medias_media_partnerships_9":"","programme_medias_media_connects_9":"","programme_medias_media_9_documents_collection":"","programme_medias_media_9_documents_file_0":"","programme_medias_media_9_documents_button_0":"","programme_medias_media_9_documents_file_1":"","programme_medias_media_9_documents_button_1":"","programme_medias_media_9_documents_file_2":"","programme_medias_media_9_documents_button_2":"","programme_medias_media_9_documents_file_3":"","programme_medias_media_9_documents_button_3":"","programme_medias_media_9_documents_file_4":"","programme_medias_media_9_documents_button_4":"","programme_medias_media_9_documents_file_5":"","programme_medias_media_9_documents_button_5":"","programme_medias_media_9_documents_file_6":"","programme_medias_media_9_documents_button_6":"","programme_medias_media_9_documents_file_7":"","programme_medias_media_9_documents_button_7":"","programme_medias_media_9_documents_file_8":"","programme_medias_media_9_documents_button_8":"","programme_medias_media_9_documents_file_9":"","programme_medias_media_9_documents_button_9":"","programme_medias_media_9_buttons_collection":"","programme_medias_media_9_buttons_text_0":"","programme_medias_media_9_buttons_url_0":"","programme_medias_media_9_buttons_text_1":"","programme_medias_media_9_buttons_url_1":"","programme_medias_media_9_buttons_text_2":"","programme_medias_media_9_buttons_url_2":"","programme_medias_media_9_buttons_text_3":"","programme_medias_media_9_buttons_url_3":"","programme_medias_media_9_buttons_text_4":"","programme_medias_media_9_buttons_url_4":"","programme_medias_media_9_buttons_text_5":"","programme_medias_media_9_buttons_url_5":"","programme_medias_media_9_buttons_text_6":"","programme_medias_media_9_buttons_url_6":"","programme_medias_media_9_buttons_text_7":"","programme_medias_media_9_buttons_url_7":"","programme_medias_media_9_buttons_text_8":"","programme_medias_media_9_buttons_url_8":"","programme_medias_media_9_buttons_text_9":"","programme_medias_media_9_buttons_url_9":"","programme_medias_media_9_social-media-url_collection":"","programme_medias_media_9_social-media-url_url_0":"","programme_medias_media_9_social-media-url_url_1":"","programme_medias_media_9_social-media-url_url_2":"","programme_medias_media_9_social-media-url_url_3":"","programme_medias_media_9_social-media-url_url_4":"","programme_medias_media_9_social-media-url_url_5":"","programme_medias_media_9_social-media-url_url_6":"","programme_medias_media_9_social-media-url_url_7":"","programme_medias_media_9_social-media-url_url_8":"","programme_medias_media_9_social-media-url_url_9":"","programme_active-campaign_campaign_collection":"","programme_active-campaign_campaign_code_0":"","programme_active-campaign_campaign_code_1":"","programme_active-campaign_campaign_code_2":"","programme_active-campaign_campaign_code_3":"","programme_active-campaign_campaign_code_4":"","programme_active-campaign_campaign_code_5":"","programme_active-campaign_campaign_code_6":"","programme_active-campaign_campaign_code_7":"","programme_active-campaign_campaign_code_8":"","programme_active-campaign_campaign_code_9":"","programme_social-media-urls_social-media-url_collection":"","programme_social-media-urls_social-media-url_url_0":"","programme_social-media-urls_social-media-url_url_1":"","programme_social-media-urls_social-media-url_url_2":"","programme_social-media-urls_social-media-url_url_3":"","programme_social-media-urls_social-media-url_url_4":"","programme_social-media-urls_social-media-url_url_5":"","programme_social-media-urls_social-media-url_url_6":"","programme_social-media-urls_social-media-url_url_7":"","programme_social-media-urls_social-media-url_url_8":"","programme_social-media-urls_social-media-url_url_9":"","programme_internal-metrics_internal-metric_collection":"","programme_internal-metrics_internal-metric_hcps-reached-out_0":"","programme_internal-metrics_internal-metric_hcps-reached-out_1":"","programme_internal-metrics_internal-metric_hcps-reached-out_2":"","programme_internal-metrics_internal-metric_hcps-reached-out_3":"","programme_internal-metrics_internal-metric_hcps-reached-out_4":"","programme_internal-metrics_internal-metric_hcps-reached-out_5":"","programme_internal-metrics_internal-metric_hcps-reached-out_6":"","programme_internal-metrics_internal-metric_hcps-reached-out_7":"","programme_internal-metrics_internal-metric_hcps-reached-out_8":"","programme_internal-metrics_internal-metric_hcps-reached-out_9":"","programme_languages_language":"","programme_languages_programme-en":"","programme_languages_programme-de":"","programme_languages_programme-fr":"","programme_languages_programme-ru":"","programme_languages_programme-es":"","programme_languages_programme-pt":"","programme_languages_programme-ja":"","programme_languages_programme-zh-CN":"","_links":{"self":[{"href":"https:\/\/test.lab.cor2ed.com\/cms\/wp-json\/wp\/v2\/programmes\/3277","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/test.lab.cor2ed.com\/cms\/wp-json\/wp\/v2\/programmes"}],"about":[{"href":"https:\/\/test.lab.cor2ed.com\/cms\/wp-json\/wp\/v2\/types\/programmes"}],"version-history":[{"count":3,"href":"https:\/\/test.lab.cor2ed.com\/cms\/wp-json\/wp\/v2\/programmes\/3277\/revisions"}],"predecessor-version":[{"id":189473,"href":"https:\/\/test.lab.cor2ed.com\/cms\/wp-json\/wp\/v2\/programmes\/3277\/revisions\/189473"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/test.lab.cor2ed.com\/cms\/wp-json\/wp\/v2\/media\/3590"}],"wp:attachment":[{"href":"https:\/\/test.lab.cor2ed.com\/cms\/wp-json\/wp\/v2\/media?parent=3277"}],"wp:term":[{"taxonomy":"labels","embeddable":true,"href":"https:\/\/test.lab.cor2ed.com\/cms\/wp-json\/wp\/v2\/labels?post=3277"},{"taxonomy":"keywords","embeddable":true,"href":"https:\/\/test.lab.cor2ed.com\/cms\/wp-json\/wp\/v2\/keywords?post=3277"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}