DDR and PARPi BluePrint documents have been developed under the guidance of a Steering Committee with expertise in the field of DDR and PARP inhibition (PARPi).


These BluePrints are a reference guide to key aspects of PARPi and DDR and their role in oncology.

A variety of topics are covered, including the role of DDR in oncology, synthetic lethality, use of PARPi in oncology, efficacy and safety of currently approved PARP inhibitors, and the role of combination therapy with PARPi.

 

 

Dr Violeta Serra has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AstraZeneca and Tesaro. 

Prof. Jonathan A. Ledermann has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AstraZeneca, Clovis, Cristal Therapeutics, Pfizer, Roche and Seattle Genetics. 

Prof. Eric Pujade-Lauraine has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AstraZeneca, Clovis, Pfizer, Roche and Tesaro. 

Prof. Simon Boulton has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

Artios Pharma Ltd.

Prof. Charlie Gourley has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AstraZeneca, Apera, Clovis, MSD, Nucana, Novartis, Roche, Sierra Oncology and Tesaro. 

Dr Judith Balmaña has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AstraZeneca. 

Prof. Sibylle Loibl has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AstraZeneca, Amgen, Novartis, Pfizer and Roche. 

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